Direct hepatic differentiation of mouse embryonic stem cells induced by valproic acid and cytokines

doi:10.3748/wjg.15.5165

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Nov 7, 2009 (publication date) through Jan 22, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 7, 2009; 15(41): 5165-5175
Published online Nov 7, 2009. doi: 10.3748/wjg.15.5165

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Figure 5 In vivo multi-differentiation potential and tumorigenic analyses. A-F: The teratomas derived from ES cells were composed of a variety of types of differentiated cells from all three primary germ layers including secretory glands (B), muscle (C), epithelium (D), neuroectodermal cells (E) and cartilage (F); G-I: The tumor-like bumps derived from ES-HPCs contained only epithelial (H) and mesenchymal-like cells, and duct-like structures (I) surrounded by several epithelial cells were also observed.

Citation: Dong XJ, Zhang GR, Zhou QJ, Pan RL, Chen Y, Xiang LX, Shao JZ. Direct hepatic differentiation of mouse embryonic stem cells induced by valproic acid and cytokines. World J Gastroenterol 2009; 15(41): 5165-5175
URL: https://www.wjgnet.com/1007-9327/full/v15/i41/5165.htm
DOI: https://dx.doi.org/10.3748/wjg.15.5165