Hepatitis C virus genotype 3a infection and hepatocellular carcinoma: Pakistan experience

Table 1 Characteristics, biochemistry and etiology of HCC patients (n = 145) n (%)

Risk factor	Value
Age ± SD (yr)	58 ± 11
Male	107 (73.79)
ALT	61 (42.1)
AST	61 (42.1)
Alkaline phosphatase	145 (100)
Bilirubin	145 (100)
AFP elevation	125 (86.2)
Cirrhosis present	98 (67.58)
HBsAg-positive (alone)	18 (12.41)
Anti-HBc-positive (alone)	2 (1.37)
Anti-HBs-positive	10 (6.89)
HBV-DNA PCR-positive (alone)	26 (17.93)
Anti-HCV-positive (alone)	92 (63.44)
HCV-RNA PCR-positive	83 (57.24)
HBV- and HCV-positive	19 (13.10)
No known etiology	6 (4.13)

HCC: Hepatocellular carcinoma; ALT: Alanine aminotransferase; AST: Aminotransferase; AFP: α-fetoprotein; HCV: Hepatitis C virus; HBV: Hepatitis B virus.