Patient-reported outcomes in subjects with neuroendocrine tumors of the pancreas

Table 2 Effects of neuroendocrine tumors of the pancreas on the SF-12 physical (PCS) and mental (MCS) component summaries estimated by means of three-way ANOVA adjusted for age (increasing trend among the age classes) and gender

	PCS		MCS
	Effects (95% CI)	P value	Effects (95% CI)	P value
Overall effects of the disease (patients vs normative group)	-1.16 (-5.66 to 3.34)	0.610	-5.32 (-10.30 to -0.35)	0.036
Effects of the disease within males	-1.17 (-8.01 to 5.68)	0.735	-6.12 (-13.69 to 1.45)	0.112
Effects of the disease within females	-1.15 (-6.99 to 4.69)	0.697	-4.53 (-10.99 to 1.93)	0.167
Interaction between the effects of the disease and gender (males vs females)	-0.02 (-9.02 to 8.97)	0.996	-1.59 (-11.54 to 8.37)	0.752
Interaction between the effects of the disease and age	3.32 (-6.96 to 13.60)	0.522	9.54 (-1.84 to 20.92)	0.099
Interaction between the effects of the disease and age within males	4.10 (-11.88 to 20.09)	0.611	9.24 (-8.44 to 26.93)	0.301
Interaction between the effects of the disease and age within females	2.54 (-10.39 to 15.48)	0.697	9.84 (-4.47 to 24.15)	0.175
Interaction between the effects of the disease and age and gender	1.56 (-19.00 to 22.12)	0.880	-0.59 (-23.35 to 22.17)	0.959

95% CI: 95% confidence interval.