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©2009 The WJG Press and Baishideng.
World J Gastroenterol. Jan 28, 2009; 15(4): 449-456
Published online Jan 28, 2009. doi: 10.3748/wjg.15.449
Published online Jan 28, 2009. doi: 10.3748/wjg.15.449
Table 2 Incidence of chemotherapy-related toxicities
| Treatment group | ||||
| CAPIRI (n = 17) | CAPIRI-Bev (n = 29) | |||
| NCI-CTC Grade | Total (1-4) | 3-4 | Total (1-4) | 3-4 |
| Hematologic toxicities, number (%) patients | ||||
| Anemia | 2 (11.8) | 1 (5.9) | 4 (13.8) | - |
| Leukopenia | 4 (23.5) | 2 (11.8) | 6 (20.7) | 1 (3.4) |
| Neutropenia | 3 (17.6) | 1 (5.9) | 5 (17.2) | 2 (6.9) |
| Non-hematologic toxicities, number (%) patients | ||||
| Diarrhea | 7 (41.2) | 5 (29.4) | 13 (44.8) | 5 (17.2) |
| Nausea/vomiting | 6 (35.3) | - | 12 (41.4) | 2 (6.9) |
| Hand-foot syndrome | 6 (35.3) | 1 (5.9) | 9 (31.0) | - |
| Mucositis | 3 (17.3) | 2 (11.8) | 5 (17.2) | - |
| Cholinergic syndrome | 3 (17.3) | - | 2 (6.9) | - |
| Alopecia1 | 2 (11.8) | - | 12 (41.4) | - |
| Fatigue | 2 (11.8) | - | 10 (34.5) | - |
| Anorexia | 1 (5.9) | 1 (5.9) | 2 (6.9) | 1 (3.4) |
| Fever | 1 (5.9) | - | 4 (13.8) | - |
| Proteinuria1 | - | - | 7 (24.1) | 1 (3.4) |
| Arterial hypertension | - | - | 3 (10.3) | - |
| Cardiovascular | 1 (5.9) | - | 1 (3.4) | 1 (3.4) |
| Thromboembolic event | - | - | 3 (10.3) | - |
| GGT rise | 1 (5.9) | - | 4 (13.8) | 4 (13.8) |
| Hypokalemia | 1 (5.9) | 1 (5.9) | 3 (10.3) | - |
| Creatinine rise | 1 (5.9) | - | 1 (3.4) | - |
- Citation: Moehler M, Sprinzl MF, Abdelfattah M, Schimanski CC, Adami B, Godderz W, Majer K, Flieger D, Teufel A, Siebler J, Hoehler T, Galle PR, Kanzler S. Capecitabine and irinotecan with and without bevacizumab for advanced colorectal cancer patients. World J Gastroenterol 2009; 15(4): 449-456
- URL: https://www.wjgnet.com/1007-9327/full/v15/i4/449.htm
- DOI: https://dx.doi.org/10.3748/wjg.15.449