Hepatoprotective evaluation of Anogeissus latifolia: In vitro and in vivo studies

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Oct 14, 2009 (publication date) through Jul 29, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 14, 2009; 15(38): 4816-4822
Published online Oct 14, 2009. doi: 10.3748/wjg.15.4816

Table 2 Effect of Anogeissus latifolia on plasma biochemical parameters and lipid peroxidation in CCl₄-intoxicated rats liver (n = 6, mean ± SE)

Treatment (n = 6)	AST (IU/L)	ALT (IU/L)	ALP (IU/L)	Lipid peroxidation nmol of MDA/mg protein
Normal	88.17 ± 5.47	54 ± 2.7	249.5 ± 18.2	4.1 ± 0.5
CCl₄ (500 μL/kg)	254.9 ± 19.3^c	222.8 ± 10.14^c	328.5 ± 25.36^a	14.8 ± 1.3^c
Liv52 (2 mL/kg)	111.7 ± 8.7^b	71.4 ± 5.6^b	255 ± 24.1^b	5.4 ± 0.6^b
ALE (300 mg/kg)	117 ± 6.7^b	66.2 ± 6.1^b	258 ± 15.54^b	6.1 ± 0.5^b

^aP < 0.01,

^cP < 0.001 vs normal;

^bP < 0.01 vs carbon tetrachloride. ALP: Alkaline phosphatase.

Citation: Pradeep HA, Khan S, Ravikumar K, Ahmed MF, Rao MS, Kiranmai M, Reddy DS, Ahamed SR, Ibrahim M. Hepatoprotective evaluation of Anogeissus latifolia: In vitro and in vivo studies. World J Gastroenterol 2009; 15(38): 4816-4822
URL: https://www.wjgnet.com/1007-9327/full/v15/i38/4816.htm
DOI: https://dx.doi.org/10.3748/wjg.15.4816