A short review of malabsorption and anemia

Table 1 Prevalence of CD in patients presenting with IDA

Study, yr	n	Positive serology (%)	Positive biopsy (%)	Comments
Corazza et al[16], 1995	200	8	5	IDA. 8.5% if only obscure IDA considered. All patients with positive serology were biopsied
Carroccio et al[17], 1998	85	5.8	5.8	IDA. 20% if only refractory obscure IDA considered. All patients with positive serology were biopsied. 80% of CD cases were women
Unsworth et al[18], 2000	483	6.6	4.6	Blood donors with anemia, most with IDA. Not all seropositive patients were biopsied. 95% of CD cases were women
Haslam et al[19], 2001	216	2.3	n/a	Pregnant women with anemia. Four of five anemic women with positive serology have IDA. Only serology was performed
Annibale et al[20], 2001	190	n/a	13.7	Obscure IDA. All patients were biopsied. 85% of CD cases were women
Howard et al[21], 2002	258	10.9	4.7	Majority of patients with previously not studied IDA (4% folate deficiency). Not all seropositive patients were biopsied. 83% of CD cases were women
Ransford et al[22], 2002	484	3.5	2.3	Previously not studied IDA. Not all seropositive patients were biopsied. 73% of CD cases were women
Grisolano et al[23], 2004	103	n/a	8.7	Previously not studied IDA. All patients were biopsied. 100% of CD cases were women
Mandal et al[24], 2004	504	n/a	1.8	IDA with normal upper gastroscopy. Not all patients were biopsied
Hershko et al[25], 2005	150	5.3	5.3	Previously not studied IDA. All seropositive patients were biopsied
Kalayci et al[26], 2005	135	4.4	4.4	Previously not studied children with IDA. All seropositive patients were biopsied
Zamani et al[27], 2008	206	15	14.6	Obscure IDA. All patients were biopsied
Carter et al[28], 2008	116	n/a	6.5	Previously not studied premenopausal women with IDA. All patients were biopsied

n/a: Not available data; IDA: Iron deficiency anemia; CD: Celiac disease.