Attenuation of portal hypertension by natural taurine in rats with liver cirrhosis

Table 3 Degrees of liver cirrhosis of rats in different experimental groups

	n	Grading of LC1
		S0	SI	SII	SIII	SIV	SV	SVI
NML	20	0	0	0	0	0	0	0
LC - NTaub	20	0	0	0	0	5	12	3
LC + NTaud	20	0	0	2	6	7	5	0

¹ Grading criteria: S0, normal structure of liver tissue, which is characterized by an absence of deposition of abnormal collagen fibers; S_I, occurrence of fibrous septa (FS) due to hyperplasia of collagen fibers in portal areas (P) or areas surrounding the central vein (C); extension of FS within 50% of the distance between two portal areas (P-P) or between portal and central vein areas (P-C); S_II, extension of fibrous septa beyond 50% of the P-P or P-C; connection of fibrous septa is either incomplete or complete; absence of completely enclosed or separated hepatic lobules; S_III, presence of completely enclosed hepatic lobules by FS; S_IV, separation of hepatic lobules by extensive hyperplasia of collagen fibers; destruction of the normal lobular structure; pseudo-lobules formed are mainly large-square-shaped (> 50%); S_V, concomitant presence of large-square- and small-round-shaped pseudo-lobules (both less than 50%); and S_VI, intrahepatic pseudo-lobules are mainly small-round-shaped (> 50%).

^bP < 0.01 vs the normal healthy control;

^dP < 0.01 vs the non-treated LC group.