Influence of paeonol on expression of COX-2 and p27 in HT-29 cells

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Sep 21, 2009 (publication date) through Dec 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 21, 2009; 15(35): 4410-4414
Published online Sep 21, 2009. doi: 10.3748/wjg.15.4410

Table 2 Rate of apoptosis, cell cycle and expression of p27 after treatment with paeonol

Paeonol concentration(mmol/L)	p27 staining intensity	p27 positive rate	Rate of apoptosis	G₀/G₁ phase	S phase	G₂/M phase
0	-	0.46	2.3	61.3	20.3	18.4
0.094	+	18.18^b	7.6^b	28.7^b	55.8^b	16.1
0.376	++	46.70^b	16.1^b	50.7^b	35.8^b	13.5^b
1.504	+++	86.86^b	34.5^b	38.0^b	45.6^b	16.4

^bP < 0.01 vs untreated control cells.

Citation: Ye JM, Deng T, Zhang JB. Influence of paeonol on expression of COX-2 and p27 in HT-29 cells. World J Gastroenterol 2009; 15(35): 4410-4414
URL: https://www.wjgnet.com/1007-9327/full/v15/i35/4410.htm
DOI: https://dx.doi.org/10.3748/wjg.15.4410