Novel ABCB11 mutations in a Thai infant with progressive familial intrahepatic cholestasis

Table 1 Evolution of clinical biochemistry test results with body weight and height

Age (mo)	ALP (U/L)1	AST (U/L) (15-37)	ALT (U/L) (30-65)	GGT (U/L)2	Alb (g/L) (34-50)	TB (mg/dL) (0-1.5)	DB (mg/dL) (0-0.5)	Chol (mg/dL) (114-203)	BW (kg)	Ht (cm)
2	417	354	264	47	37.4	5.7	3.9	155	4.95	56.0
6	298	375	344	37	49.8	7.7	6.4	229	7.20	64.0
12	267	472	354	66	33.8	5.3	4.5	191	8.20	68.0
18	332	311	237	59	38.1	6.2	5.2	151	10.4	71.4
24	269	239	171	59	44.1	6.1	4.5	121	11.4	78.0
30	373	340	240	60	41.2	7.9	6.8	102	11.5	80.0

ALP: Alkaline phosphatase; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; Alb: Albumin; TB: Total bilirubin; DB: Direct bilirubin; Chol: Cholesterol; BW: Body weight; Ht: Height. Units and expected ranges for test-result values are given in parentheses.

¹Normal values for female children < 1 year, 185-555; 1-2 years, 185-520; 3 years, 185-425 U/L[17];

²Normal values for children 1-2 mo, 12-123; 2-4 mo, 8-90; 4 mo-10 years, 5-32 U/L[18].