Review
Copyright ©2009 The WJG Press and Baishideng.
World J Gastroenterol. Sep 14, 2009; 15(34): 4240-4262
Published online Sep 14, 2009. doi: 10.3748/wjg.15.4240
Table 2 Known risk factors for cholangiocarcinomas
General risk factors
Old age (older than 65 years)
Smoking
Obesity
Diabetes
Post surgical
Biliary-enteric anastomosis
Chronic inflammatory diseases
Primary sclerosing cholangitis (PSC)
Hepatolithiasis (Oriental Cholangiohepatitis)
Hepatitis C
Hepatitis B
Human Immunodeficiency Virus (HIV)
Liver cirrhosis
Parasitic infections
Opisthorchis viverrini
Clonorchis sinensis
Congenital
Choledochal cysts
Caroli’s disease
Congenital hepatic fibrosis
Chemical agents
Thorotrast
Dioxin
Nitrosamines
Asbestos
Medications
Oral Contraceptive Pills
Isoniazid