Overview of immunosuppression in liver transplantation

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Sep 14, 2009 (publication date) through Feb 8, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 14, 2009; 15(34): 4225-4233
Published online Sep 14, 2009. doi: 10.3748/wjg.15.4225

Table 1 Drugs that increase CNI and sirolimus levels

Drugs that increase CNI levels

Macrolides: clarithromycin, erythromycin, azithromycin

Antifungals: fluconazole, itraconazole, ketoconazole, voriconazole, clotrimazole

Calcium channel blockers: verapamil, diltiazem, nifedipine

Others: cisapride, metaclopramide, amiodarone, cimetidine, protease inhibitors

Drugs that decrease CNI and sirolimus levels

Antibiotics: rifabutin, rifampin

Anticonvulsants: carbamazepine, phenobarbital, phenytoin, fosphenytoin

Others: St. John’s Wort

CNI: Calcineurin inhibitor.

Citation: Pillai AA, Levitsky J. Overview of immunosuppression in liver transplantation. World J Gastroenterol 2009; 15(34): 4225-4233
URL: https://www.wjgnet.com/1007-9327/full/v15/i34/4225.htm
DOI: https://dx.doi.org/10.3748/wjg.15.4225