Dysregulation of gastric H,K-ATPase by cigarette smoke extract

Figure 3 Gastric mucosal tissue sections of control (A, C) and smoke-treated (B, D) mice. A and B demonstrate the gastric mucosae of control and treated mice stained with periodic acid-Schiff and hematoxylin. No difference is noted in parietal cells of control and treated tissues. Immunohistochemical labeling of parietal cells in the gastric mucosa of control (C) and smoke-treated (D) mice with antibodies specific for H,K-ATPase β-subunit. Labeled parietal cells are distributed throughout the gastric glands. Note the difference in the labeling intensity of parietal cells in control vs smoke-treated mice, × 400.