Overexpression of β3/γ2 chains of laminin-5 and MMP7 in biliary cancer

Figure 4 MMP7 expression in biliary tract cancer tissues. A, B: Extrahepatic bile duct cancer tissues; A: Moderately differentiated tubular adenocarcinoma positive for staining. Note that MMP7 is strongly positive in tumor cells at the invasive front; B: Papillary adenocarcinoma negative for staining; C, D: Gallbladder cancer tissues; C: Moderately differentiated tubular adenocarcinoma positive for staining; D: Well differentiated tubular adenocarcinoma negative for staining; E, F: Carcinoma tissues of the ampulla of Vater; E: Moderately differentiated tubular adenocarcinoma positive for staining. Note that MMP7 is strongly positive in tumor cells at the invasive front; F: Well differentiated tubular adenocarcinoma negative for staining.