Therapy of central pontine myelinolysis following living donor liver transplantation: Report of three cases

Table 1 Blood electrolytes, Child-Turcotte-Pugh (CTP) score, and “Model for end-stage liver disease” (MELD) score

	Case 1	Case 2	Case 3
Pre-operative serum sodium (mmol/L)	124	119	119
Post-operative serum sodium (mmol/L)	151	153	141
Pre-operative serum magnesium (mmol/L)	0.52	0.47	0.64
Post-operative serum magnesium (mmol/L)	0.58	0.62	0.68
Pre-operative plasma osmotic pressure (mOsm/kg H2O)	238.71	232.47	258.45
Post-operative plasma osmotic pressure (mOsm/kg H2O)	295.36	288.93	291.92
Plasma cholesterol (mmol/L)	0.18	1.24	1.07
CTP score	B	C	C
MELD score	30	36	35
Cyclosporine A or Fk506 concentration	Cyclosporine A 180-250 mg/L	FK506 6.5-8 ng/mL	No
Clinical manifestations	Locked-in syndrome	Coma	Coma
Special therapy	Gamma globulin (i.v.)	Hyperbaric oxygen treatment	No