Endotoxin receptor CD14 gene variants and histological features in chronic HCV infection

Table 1 Epidemiological characteristics of chronic hepatitis C patients with regard to CD14 rs2569190 genotype (UMG group)

	n	CD14 rs2569190 genotype				MAF	P
		CC	CT	TT	P
Total number (%)	137	30 (21.9)	70 (51.1)	37 (27)	0.8651	0.526
Gender (Female/male)	60/77	11/19	36/34	13/24	0.2142	0.517/0.532	0.7953
Age (mean ± SD)		46.5 ± 13.1	45.3 ± 10.8	39.6 ± 12.5	0.008a
HCV subtype
1a	31	7 (22.6)	17 (54.8)	7 (22.6)
1b	73	18 (24.7)	38 (52.0)	17 (23.3)		0.500
1a + 1b	6	1 (16.7)	3 (50.0)	2 (33.3)
					0.073b		0.0873
2a	1	0	0	1 (100.0)
2b	4	2 (50.0)	1 (25.0)	1 (25.0)		0.630
3a	22	2 (16.7)	11 (50.0)	9 (33.3)

MAF: Minor allele frequency.

¹Exact test for the Hardy-Weinberg equilibrium;

²C carriers vs TT (χ² test);

³χ² test was applied;

^aC carriers vs TT (independent samples t-test);

^bC carriers vs TT, HCV type 1 vs non-type 1 infections (χ² test).