Secondary hepatic resection as a therapeutic goal in advanced colorectal cancer

Table 1 Outcomes related to secondary hepatic resection in patients treated with oxaliplatin-based chemotherapy

Study	n	Regimen	Response rate (%)	Resection rate (%)	R0 rate (%)	MS (mo)
Unselected populations
GERCOR[14]	111	FOLFOX6	54.0	22.0	13.0	NYR
Tournigand et al[24]	311	FOLFOX4	58.5	17.7	11.3	38.9
Tournigand et al[24]	309	FOLFOX71	59.2	15.2	9.4	43.0
Colucci et al[23]	182	FOLFOX4	34.0	4.4	NR	NR
Liver metastases only
Alberts et al[25]	44	FOLFOX4	60.0	40.0	33.3	NR

¹FOLFOX7 × 6 cycles, followed by treatment without oxaliplatin × 12 cycles, followed by FOLFOX7 until PD. MS: Median survival in resected patients; FOLFOX: Oxaliplatin plus infusional 5-fluorouracil/leucovorin (5-FU/LV); NYR: Not yet reached; NR: Not reported.