No association between phosphatase and tensin homolog genetic polymorphisms and colon cancer

Table 3 PTEN haplotype associations with colon cancer n (%)

Haplotype3	Frequency	Cases	Controls	Base model1			Full model2
				OR	95% CI	P	OR	95% CI	P
A-G-T-C	0.180	146 (48.2)	157 (51.8)	1.16	0.865-1.550	0.32	1.05	0.751-1.456	0.79
C-C-T-C	0.079	53 (48.2)	57 (51.8)	0.98	0.643-1.485	0.91	1.04	0.642-1.669	0.89
C-G-C-C	0.184	88 (42.1)	121 (57.9)	0.76	0.548-1.060	0.11	0.94	0.645-1.356	0.72
C-G-C-T	0.151	71 (52.6)	64 (47.4)	1.44	0.979-0.106	0.06	1.31	0.849-2.029	0.22
C-G-T-C	0.398	58 (41.1)	83 (58.9)	0.75	0.510-1.089	0.13	0.70	0.449-1.082	0.11

¹Base model adjusted for age, gender and race;

²Full model further adjusted for BMI, family history of colorectal cancer, NSAID use, and physical activity based on 329 cases and 390 controls;

³Five other haplotypes representing a total of six participants were removed due to rarity.