Phenotypic changes of human cells in human-rat liver during partial hepatectomy-induced regeneration

Figure 4 Proliferative activities of hHLCs during PHx-induced liver regeneration in HRC. Immunostaining for PCNA, a marker for cell proliferation, was performed to evaluate the proliferation of hHLCs. An antibody against PCNA antigen was used to evaluate the percentage of hepatocytes in the regenerative process after 70% hepatectomy. Ten days after PHx, PCNA staining demonstrated the active proliferation of hHLCs in the PHx group (II) compared with the control group (I).