Perianal disease, small bowel disease, smoking, prior steroid or early azathioprine/biological therapy are predictors of disease behavior change in patients with Crohn’s disease

Table 3 Logistic regression: predictive factors for behavior change from non-stricturing, non-penetrating to complicated disease behavior in Crohn’s disease

Factor	Coefficient	P-value	OR	95% CI
Disease location	-0.385	0.13	-	-
Longer disease duration (≤ 10 yr vs > 10 yr)	1.476	< 0.001	4.37	2.04-9.38
Perianal disease	1.351	0.001	3.86	1.72-8.67
Frequent relapses	0.388	0.404	-	-
Smoking	1.015	0.009	2.76	1.29-5.89
Steroid use	2.089	0.01	8.07	1.64-39.7
Early azathioprine use	-1.055	0.006	0.35	0.16-074

The coefficient is equivalent to the natural log of the OR.