Cyclooxygenase-2 polymorphisms and the risk of esophageal adeno- or squamous cell carcinoma

doi:10.3748/wjg.15.3493

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 28, 2009; 15(28): 3493-3497
Published online Jul 28, 2009. doi: 10.3748/wjg.15.3493

Table 3 COX-2 haplotype distribution and corresponding ORs in patients with oesophageal adenocarcinoma or squamous cell carcinoma carcinoma versus controls

Haplotype COX-2	Adenocarcinoma		Squamous cell carcinoma		Controls n = 236 (%)
Haplotype COX-2	n= 163 (%)	OR (95% CI)	n= 59 (%)	OR (95% CI)	Controls n = 236 (%)
AG/AG	59 (36.2)	Reference	18 (30.5)	Reference	94 (39.8)
AG/AC	29 (17.8)	0.87 (0.50-1.52)	12 (20.3)	1.18 (0.53-2.64)	53 (22.4)
AC/AC	5 (3.1)	1.33 (0.39-4.55)	2 (3.4)	1.74 (0.33-9.32)	6 (2.5)
GC/AC	0 (0)	-	0 (0)	-	0 (0)
GG/AC	17 (10.4)	1.29 (0.63-2.64)	4 (6.8)	0.99 (0.31-3.24)	21 (8.9)
GG/AG	40 (24.5)	1.14 (0.68-1.91)	19 (32.2)	1.77 (0.86-3.66)	56 (23.7)
GG/GG	13 (8.0)	3.45 (1.24-9.58)	4 (6.8)	3.48 (0.89-13.6)	6 (2.5)

Citation: Kristinsson JO, Westerveld PV, Morsche RHT, Roelofs HM, Wobbes T, Witteman BJ, Tan AC, Oijen MGV, Jansen JB, Peters WH. Cyclooxygenase-2 polymorphisms and the risk of esophageal adeno- or squamous cell carcinoma. World J Gastroenterol 2009; 15(28): 3493-3497
URL: https://www.wjgnet.com/1007-9327/full/v15/i28/3493.htm
DOI: https://dx.doi.org/10.3748/wjg.15.3493