Applicability and variability of liver stiffness measurements according to probe position

Table 5 Strength of concordance between LSM and FibroTest (FT) according to positions

Position (No. of patients)	Method assessing	Kappa
	Discordance rate (%)
Quantitative concordance	Spearman mean (95% CI)	Intra class coefficient mean (95% CI)
All positions applicable
Reference (196)	0.46 (0.34-0.56)	0.55 (0.33-0.67)
Anterior (196)	0.46 (0.34-0.56)	0.56 (0.34-0.68)
Lower (196)	0.40 (0.27-0.51)	0.50 (0.38-0.62)
Mean of positions (196)	0.47 (0.35-0.57)	0.56 (0.34-0.68)
At least one position applicable
Reference (306)	0.44 (0.35-0.53)	0.51 (0.39-0.63)
Anterior (357)	0.46 (0.38-0.54)	0.54 (0.32-0.66)
Lower (302)	0.39 (0.29-0.49)	0.50 (0.38-0.62)
Two classes concordance	Discordance rate n (%)	Kappa mean (SE)
Cutoff 7.1 kPa
All positions applicable
Reference (196)	66 (33.6)a	0.30 (0.07)
Anterior (196)	61 (31.1)	0.32 (0.07)
Lower (196)	71 (36.2)	0.24 (0.07)
Mean of positions (196)	67 (34.2)	0.28 (0.07)
At least one position applicable
Reference (306)	107 (34.9)b	0.28 (0.06)
Anterior (357)	112 (31.6)	0.33 (0.05)
Lower (302)	109 (36.1)c	0.24 (0.06)
Cutoff 8.8 kPa
All positions applicable
Reference (196)	46 (23.5)a	0.45 (0.07)
Anterior (196)	54 (27.6)	0.33 (0.07)
Lower (196)	56 (28.6)	0.34 (0.07)
Mean of positions (196)	52 (26.5)	0.37 (0.07)
At least one position applicable
Reference (306)	82 (26.8)b	0.38 (0.06)
Anterior (357)	108 (30.2)	0.30 (0.05)
Lower (302)	84 (27.8)c	0.34 (0.06)

^a,b,cP = 0.03 between 7.1 and 8.8 kPa.