Psychometrics of the chronic liver disease questionnaire for Southern Chinese patients with chronic hepatitis B virus infection

Table 2 Distribution of the Chinese (HK) CLDQ and SF-36v2 Health Survey scores¹

	Uncomplicated CHB2 (n = 72)				Complicated CHB2 (n = 78)				Overall (n = 150)
	Mean	(SD)	% floor3	% ceiling4	Mean	(SD)	% floor	% ceiling	Mean	(SD)	% floor	% ceiling	ES5
CLDQ
AS	6.3	(1.0)	0.0	47.2	5.6	(1.5)	0.0	28.2	5.9	(1.3)	0.0	37.3	0.5a
FA	5.2	(1.1)	0.0	6.9	4.6	(1.5)	0.0	5.1	4.9	(1.4)	0.0	6.0	0.4a
SS	5.8	(1.0)	0.0	19.4	5.2	(1.2)	0.0	6.4	5.5	(1.2)	0.0	12.7	0.5a
AC	6.2	(1.1)	0.0	48.6	5.4	(1.6)	0.0	28.2	5.8	(1.4)	0.0	38.0	0.6a
EF	5.5	(1.0)	0.0	8.3	5.0	(1.4)	0.0	5.1	5.2	(1.3)	0.0	6.7	0.4a
WO	5.9	(1.3)	1.4	37.5	5.0	(1.7)	0.0	17.9	5.4	(1.6)	0.7	27.3	0.6a
Overall	5.8	(0.8)	0.0	0.0	5.1	(1.2)	0.0	1.3	5.4	(1.1)	0.0	0.7	0.6a
SF-36v2 Health survey (HK norm)
PF (90.6)	89.0	(14.7)	0.0	34.7	80.4b	(15.4)	0.0	10.3	84.5	(15.6)	0.0	22.0	0.5a
RP (90.2)	83.6b	(21.0)	0.0	45.8	63.9b	(29.4)	1.3	24.4	73.4	(27.4)	0.7	34.7	0.7a
BP (82.6)	72.6b	(23.0)	0.0	31.9	70.1b	(28.6)	1.3	38.5	71.3	(26.0)	0.7	35.3	0.1
GH (53.2)	53.8	(21.7)	0.0	0.0	46.9b	(25.6)	0.0	2.6	50.2	(24.0)	0.0	1.3	0.3
VT (60.2)	63.9	(19.8)	1.4	1.4	58.0	(26.5)	5.1	5.1	60.8	(23.6)	3.3	3.3	0.2
SF (92.4)	86.1b	(19.3)	0.0	48.6	71.6b	(29.0)	1.3	35.9	78.6	(25.8)	0.7	42.0	0.6a
RE (88.5)	80.4b	(19.8)	0.0	36.1	75.0b	(26.9)	0.0	33.3	77.6	(23.8)	0.0	34.7	0.2
MH (72.0)	73.6	(18.4)	0.0	5.6	70.4	(21.9)	0.0	11.5	72.0	(20.3)	0.0	8.7	0.2
PCS (50)	46.4b	(9.9)	0.0	0.0	39.5b	(12.2)	0.0	0.0	42.8	(11.6)	0.0	0.0	0.6a
MCS (50)	50.1	(10.4)	0.0	0.0	47.8	(13.9)	0.0	0.0	48.9	(12.3)	0.0	0.0	0.2

AS: Abdominal Symptoms; FA: Fatigue; SS: Systemic Symptoms; AC: Activity; EF: Emotional Function; WO: Worry; PF: Physical Functioning; RP: Role Physical; BP: Bodily Pain; GH: General Health; VT: Vitality; SF: Social Functioning; RE: Role Emotional; MH: Mental Health; PCS: Physical Component Summary; MCS: Mental Component Summary; ES: Effect Size. ¹The Chinese (HK) CLDQ score range 1-7 and SF-36v2 score range 0-100; higher scores indicate better health-related quality of life;

²Uncomplicated CHB are patients who had no cirrhosis or hepatocellular carcinoma (HCC) and normal liver function; Complicated CHB refers to those with cirrhosis or HCC;

³% floor: Percentage of CHB patients at the lowest possible score;

⁴% ceiling: Percentage of CHB patients at the highest possible score;

⁵Effect size was calculated as the difference between uncomplicated and complicated mean score, divided by the overall SD.

^aSignificant difference between uncomplicated and complicated CHB patients by independent sample t (P < 0.05);

^bSignificant difference between CHB groups and HK norm by independent sample t (P < 0.05).