Characteristics of common solid liver lesions and recommendations for diagnostic workup

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Jul 14, 2009 (publication date) through Dec 2, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 14, 2009; 15(26): 3217-3227
Published online Jul 14, 2009. doi: 10.3748/wjg.15.3217

Table 3 Immunohistochemical staining in the evaluation of hepatic tumors

Tumor	Recommended immunostaining
HCC	Polyclonal CEA
	Cytokeratin 8/18 pair (+/+ staining)
	Cytokeratin 7/20 pair(-/- staining)
	Hep Par 1, AFP
Cholangiocarcinoma	Cytokeratin 7/19 pair (+/+ staining)
	Cytokeratin 7/20 pair (+/- staining)
	B-HCG, CEA, Mucin-1
Epithelioid hemangioendothelioma	CD34
	CD31
	Factor VIII
Angiomyolipoma	HMB-45, smooth muscle actin
Metastatic carcinoma
Neuroendocrine	Chromagin, synaptophysin, neural enolase
Pancreas	Cytokeratin 7/20 pair (+/+ staining)
Colorectal	Cytokeratin 7/20 pair( -/+ staining)
Breast	Cytokeratin 7/20 pair (+/- staining)
Lung	Cytokeratin 7/20 pair (+/- staining)

Citation: Assy N, Nasser G, Djibre A, Beniashvili Z, Elias S, Zidan J. Characteristics of common solid liver lesions and recommendations for diagnostic workup. World J Gastroenterol 2009; 15(26): 3217-3227
URL: https://www.wjgnet.com/1007-9327/full/v15/i26/3217.htm
DOI: https://dx.doi.org/10.3748/wjg.15.3217