Nanosized As2O3/Fe2O3 complexes combined with magnetic fluid hyperthermia selectively target liver cancer cells

Table 5 Results of acute toxicity test of As₂O₃/Fe₂O₃

Groups	Dose (g/kg)	Log	N	Deaths (N)	Mortality % (p)	Survival % (q)	p×q
1	10.00	1.000	10	10	100	0	0.00
2	7.07	0.849	10	5	50	50	0.25
3	5.00	0.699	10	3	30	70	0.21
4	3.50	0.544	10	3	30	70	0.21
5	2.50	0.398	10	1	10	90	0.09
6	1.75	0.243	10	0	0	100	0.00
	i = 0.15			∑p = 2.2

lgLD₅₀ = 1-0.15 (2.2-0.5) = 0.745, Sm = 0.0414, As₂O₃/Fe₂O₃ Lg LD₅₀ and its 95% CI: 0.745 ± 1.96 × 0.0414 = 0.745 ± 0.0811, As₂O₃/Fe₂O₃ LD₅₀ and its 95% CI: 5.56 g/kg (4.56-6.70 g/kg).