Brief Articles
Copyright ©2009 The WJG Press and Baishideng.
World J Gastroenterol. Jun 21, 2009; 15(23): 2913-2917
Published online Jun 21, 2009. doi: 10.3748/wjg.15.2913
Table 2 Mean values of every follow-up time point in the study groups (mean ± SD)
Variable (n = 143)Group 1 (n = 73)Group 2 (n = 40)Group 3 (n = 30)Group 4 (n = 5)
GFR (mL/min per 1.73 m2)97.4 ± 12.785.6 ± 17.962.3 ± 20.549.6 ± 20.2
The declining percentage of GFR from baseline (%)7.3 ± 2.616.7 ± 10.1ac32.5 ± 12.9ac52.4 ± 20.8ac
SCr (&mgr;mol/L)76.3 ± 16.283.7 ± 15.490.3 ± 19.8173.7 ± 28.5ac
BUN (mmol/L)5.8 ± 1.76.3 ± 1.26.9 ± 1.511.2 ± 2.6ac
Dosage (mg/kg per day)
Cyclosporine A2.5 ± 0.83.0 ± 1.03.3 ± 0.93.8 ± 1.1a
Tacrolimus0.049 ± 0.030.052 ± 0.070.054 ± 0.050.058 ± 0.03a
Trough levels
Cyclosporine A (ng/mL)145.2 ± 30.5154.8 ± 25.6165.3 ± 39.4183.2 ± 31.2a
Tacrolimus (ng/mL)5.1 ± 0.85.5 ± 1.26.2 ± 1.0a6.8 ± 1.3ac
Diabetes (%)9.210.59.311.1
Hypertension (%)38.534.237.233.3
Follow-up time, mean (range, mo)35.6 (23-36)33.7 (24-36)30.4 (19-36)27.8 (16-36)
Microproteinuria
β2m (mg/L)0.2 ± 0.10.4 ± 0.2a1.0 ± 1.3ac4.2 ± 2.5ac
α1m (mg/L)22.6 ± 21.138.9 ± 25.4a42.3 ± 35.9ac65.1 ± 30.4ac
Microalbumin (mg/L)46.9 ± 26.283.6 ± 55.5a70.9 ± 33.845.4 ± 32.9
Immunoglobulin (mg/L)23.9 ± 14.621.5 ± 29.137.3 ± 26.433.5 ± 29.1
Transferrin (mg/L)3.2 ± 10.210.8 ± 27.88.2 ± 15.98.1 ± 12.4