Biochemical metabolic changes assessed by 31P magnetic resonance spectroscopy after radiation-induced hepatic injury in rabbits

Table 3 Relative quantification of metabolites in rabbit liver with the pathological evaluation method

Metabolite	Control group (n = 10)	Pathological mild group (n = 12)	Pathological moderate group (n = 11)	Pathological severe group (n = 7)	F	P
PME	0.86 ± 0.23j	0.82 ± 0.35	0.79 ± 0.24	0.60 ± 0.21a	1.861	0.154
PDE	2.27 ± 0.62	2.08 ± 0.47g	2.67 ± 0.38dk	1.92 ± 0.83h	1.118	0.355
Pi	0.74 ± 0.18k	0.61 ± 0.24	0.7 ± 0.33j	0.43 ± 0.14bg	2.334	0.090
ATP	1.83 ± 0.33dil	1.58 ± 0.25agl	1.32 ± 0.07cdk	1.02 ± 0.18cfh	22.878	0.000
PME/PDE	0.36 ± 0.12	0.40 ± 0.18	0.31 ± 0.13	0.45 ± 0.48	0.189	0.903
PME/ATP	0.50 ± 0.11h	0.51 ± 0.19i	0.60 ± 0.18bf	0.59 ± 0.22	1.412	0.255
PDE/ATP	1.43 ± 0.31h	1.34 ± 0.33ij	2.04 ± 0.36bf	1.83 ± 0.72d	4.082	0.014
Pi/ATP	0.40 ± 0.09	0.39 ± 0.15	0.54 ± 0.26	0.43 ± 0.16	0.601	0.619
PME/Pi	1.47 ± 0.65	1.57 ± 0.97	1.44 ± 1.03	1.61 ± 0.75	0.316	0.814
PDE/Pi	3.46 ± 1.15	4.12 ± 2.36	4.87 ± 2.63	5.09 ± 3.24	0.810	0.497

^aP < 0.05,

^bP < 0.01,

^cP < 0.005 vs control group;

^dP < 0.05, ^eP < 0.01,

^fP < 0.005 vs mild group;

^gP < 0.05,

^hP < 0.01,

ⁱP < 0.005 vs moderate group;

^jP < 0.05,

^kP < 0.01,

^lP < 0.005 vs severe group.