Biochemical metabolic changes assessed by 31P magnetic resonance spectroscopy after radiation-induced hepatic injury in rabbits

Table 2 Relative quantification of metabolites in rabbit liver using the LDS evaluation method (mean ± SD)

Metabolite	Control group (n = 10)	LDS-mild group (n = 13)	LDS-moderate group (n = 9)	LDS-severe group (n = 8)	F	P
PME	0.86 ± 0.23j	0.79 ± 0.33	0.80 ± 0.22	0.58 ± 0.22a	1.852	0.155
PDE	2.27 ± 0.62	2.14 ± 0.51	2.48 ± 0.63	1.99 ± 0.88	3.023	0.042
Pi	0.74 ± 0.18j	0.63 ± 0.28	0.62 ± 0.29	0.43 ± 0.14a	3.475	0.026
ATP	1.83 ± 0.33eil	1.55 ± 0.24bhl	1.27 ± 0.09cej	0.98 ± 0.18cfg	22.647	0.000
PME/PDE	0.36 ± 0.12	0.39 ± 0.18	0.35 ± 0.14	0.44 ± 0.54	0.462	0.710
PME/ATP	0.50 ± 0.11	0.50 ± 0.18	0.62 ± 0.15	0.61 ± 0.25	0.990	0.409
PDE/ATP	1.43 ± 0.31gj	1.40 ± 0.38gj	1.94 ± 0.50ad	1.96 ± 0.72ad	5.080	0.005
Pi /ATP	0.40 ± 0.09	0.41 ± 0.19	0.49 ± 0.24	0.46 ± 0.16	1.582	0.211
PME/Pi	1.47 ± 0.65	1.49 ± 0.92	1.76 ± 1.12	1.39 ± 0.58	0.081	0.970
PDE/Pi	3.46 ± 1.15	4.26 ± 2.58	4.91 ± 2.65	5.05 ± 3.18	0.902	0.450

^aP < 0.05,

^bP < 0.01,

^cP < 0.005 vs control group;

^dP < 0.05,

^eP < 0.01,

^fP < 0.005 vs mild group;

^gP < 0.05,

^hP < 0.01,

ⁱP < 0.005 vs moderate group;

^jP < 0.05, ^kP < 0.01,

^lP < 0.005 vs severe group.