Nutritional status and nutritional therapy in inflammatory bowel diseases

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Jun 7, 2009 (publication date) through Nov 21, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 7, 2009; 15(21): 2570-2578
Published online Jun 7, 2009. doi: 10.3748/wjg.15.2570

Table 4 Pathophysiology of growth failure in children with IBD

Ethiopathogenesis	Mechanism
Energy and nutrient deficiencies[30]	Deficits of energy, macronutrients and micronutrients
Inflammation/proinflammatory cytokines[31]	Anorexigenic effect
	GH-IGF1 axis effects
	Bone metabolism disturbance
	Hypermetabolic/catabolic effects
Disease severity and disease location[32 33]	Severe disease
Disease severity and disease location[32 33]	Jejunal localization
Abnormal bone metabolism[34]	Effect of pro-inflammatory cytokines
	GH-IGF1 axis dysfunction
	Calcium and vitamin D deficiency
	Delayed sexual maturation
	Corticosteroids
Delayed onset of sexual maturation[35]	Hypogonadism
Abnormal IGF1 axis[36]	Low IGF1 and IGF1-BP
Abnormal IGF1 axis[36]	Proinflammatory cytokines
Drugs[28]	Corticosteroids

Citation: Hartman C, Eliakim R, Shamir R. Nutritional status and nutritional therapy in inflammatory bowel diseases. World J Gastroenterol 2009; 15(21): 2570-2578
URL: https://www.wjgnet.com/1007-9327/full/v15/i21/2570.htm
DOI: https://dx.doi.org/10.3748/wjg.15.2570