Nicotine enhances migration and invasion of human esophageal squamous carcinoma cells which is inhibited by nimesulide

doi:10.3748/wjg.15.2500

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May 28, 2009 (publication date) through Dec 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 28, 2009; 15(20): 2500-2505
Published online May 28, 2009. doi: 10.3748/wjg.15.2500

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Figure 4 A Gelatin zymography of MMP-2 activity of TE-13. A: Effect of nicotine on MMP-2 activity of TE-13 cells. Our study showed nicotine increased the activity of MMP-2. 1: DMSO; 2: Nicotine 100 &mgr;g/mL; 3: Nicotine 200 &mgr;g/mL; B: Effect of nimesulide on MMP-2 activity of TE-13 cells treated by nicotine. Our study showed nimesulide suppressed the effect of nicotine that increased the activity of MMP-2. 1: DMSO; 2: Nicotine 200 &mgr;g/mL; 3: Nicotine 200 &mgr;g/mL + Nimesulide 100 mmol/L.

Citation: Zong Y, Zhang ST, Zhu ST. Nicotine enhances migration and invasion of human esophageal squamous carcinoma cells which is inhibited by nimesulide. World J Gastroenterol 2009; 15(20): 2500-2505
URL: https://www.wjgnet.com/1007-9327/full/v15/i20/2500.htm
DOI: https://dx.doi.org/10.3748/wjg.15.2500