Nicotine enhances migration and invasion of human esophageal squamous carcinoma cells which is inhibited by nimesulide

Figure 1 Effect of nicotine on the motility (A) and invasiveness (B) of the esophageal squamous carcinoma cell line TE-13. Numbers of TE-13 cells which migrated through the polycarbonate (A) or matrigel (B) membrane of Transwell^® to the lower surface of the membrane were counted under a light microscope (× 400). Columns, mean of three triplicate experiments; bars, standard error of mean. ^bP < 0.01 vs the control group; ^dP < 0.01 vs the nicotine 100 mg/mL group.