Common immunologic mechanisms in inflammatory bowel disease and spondylarthropathies

Figure 1 The heterogeneous expression of adhesion molecules allows T cells activated in the gut to home into the joints. CCR9: Chemokine receptor-9; CCL-25: Chemokine ligand-25; MadCAM1: Mucosal addressin cell-adhesion molecule-1; VCAM1: Vascular cell adhesion molecule-1; ICAM :Intracellular adhesion molecule; VLA-4: Very late antigen-4; LFA-1: Lymphocyte function associated antigen-1; VAP-1: Vascular adhesion protein-1.