Relationship between angiotensin-(1-7) and angiotensin II correlates with hemodynamic changes in human liver cirrhosis

Table 1 Subject characteristics and casual measurements

Characteristics and measurements	Mild to moderate liver disease (MLD)	Advanced liver disease (ALD)	ALD during Liver transplantation (LT)
	n= 8	n= 7	n= 9
Age (yr)	55.5 ± 1.8	54 ± 5	50 ± 3
Sex, male/female	3 (37.5%)/5 (62.5%)	4 (57%)/3 (43%)	7 (78%)/2 (22%)
Child Pugh Score	6.7 ± 0.2	11 ± 0.8a	11 ± 1.8a
Albumin, g/dL	2.9 ± 0.15	2.4 ± 0.3	2.6 ± 0.2
Bilirubin, mg/dL	2.4 (1.7-5.9)	2.5 (1.2-7.1)	3.3 (2.0-5.5)
Creatinine, mg/dL	0.70 (0.70-0.80)	1.0 (1.0-1.45)a	1.0 (0.75-1.50)
INR (International normalization ratio)	1.2 ± 0.07	1.7 ± 0.3	1.8 ± 0.2
Prothrombin activity	68.3% ± 7.5%	50% ± 12%	42% ± 7%a
Serum Na+, mEq/L	139 ± 2	126 ± 3a	130 ± 2a

Data are expressed as mean ± SE or median (25 and 75 percentile), except for sex where number of patients and percentages are shown.

^aP < 0.05 for the comparison of the ALD and LT groups with the MLD group (ANOVA followed by Bonferroni test for mean comparisons and Kruskal-Wallis followed by the Dunn test for median comparisons). No statistical differences were detected between the ALD and LT groups.