New techniques in the tissue diagnosis of gastrointestinal neuromuscular diseases

Figure 5 Radioimmunoprecipitation assays of sera from patients with GINMD and negative and positive controls. Assays for antineuronal antibodies directed to anti-voltage-gated calcium (anti-VGCC P/Q-type) and potassium channels (VGKC) are shown. Four IP sera are weakly positive for anti-VGCC P/Q-type antibodies, and 2 STC sera strongly positive for anti-VGKC (arrowed). Dotted line: mean + 3SD; HC: Healthy controls; LEMS: Lambert-Eaton myasthenic syndrome; STC: Slow transit constipation; IP: Intestinal pseudo-obstruction; IMC: Idiopathic megacolon; NMT: Neuromyotonia.