Polymorphisms of alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 and esophageal cancer risk in Southeast Chinese males

Table 4 Analysis of ALDH2 and ADH2 genotypes and risk of esophageal cancer with reference to drinking habits

Genotypes		Non-drinker			Drinker
		Cases	Controls	OR1 (95% CI)	Cases	Controls	OR1 (95% CI)
ALDH2
G/G		26	42	1.00	64	72	1.00
G/A		43	44	1.29 (0.65-2.55)	46	22	2.47 (1.27-4.82)
A/A		27	8	4.67 (1.63-13.38)	15	3	8.63 (2.07-35.95)
G/A+A/A		70	52	1.78 (0.94-3.37)	61	25	3.08 (1.65-5.78)
ADH2
A/A		50	53	1.00	56	55	1.00
G/A		42	38	1.31 (0.70-2.46)	54	37	1.18 (0.64-2.16)
G/G		4	3	2.10 (0.35-12.54)	15	5	2.90 (0.85-9.90)
G/A+G/G		46	41	1.37 (0.74-2.54)	69	42	1.36 (0.76-2.43)
ALDH2	ADH2
G/G	A/A	10	28	1.00	34	40	2.02 (0.79-5.17)
G/A+A/A	G/A+G/G	30	27	2.84 (1.10-7.31)	39	10	8.36 (2.98-23.46)

¹ORs were adjusted for income.