Bile-acid-activated farnesoid X receptor regulates hydrogen sulfide production and hepatic microcirculation

doi:10.3748/wjg.15.2097

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May 7, 2009 (publication date) through Nov 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 7, 2009; 15(17): 2097-2108
Published online May 7, 2009. doi: 10.3748/wjg.15.2097

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Figure 7 FXR activation induces both CSE mRNA expression and activity in rats with liver cirrhosis. Quantitative real-time PCR of (A) FXR mRNA, (B) CSE mRNA, (C) SHP mRNA, (D) α1-collagen mRNA, (E) αSMA mRNA from rats liver homogenates and (F) Rat liver CSE activity. Data are mean ± SD of six mice. ^aP < 0.05 versus control rats. ^cP < 0.05 versus CCl₄ rats.

Citation: Renga B, Mencarelli A, Migliorati M, Distrutti E, Fiorucci S. Bile-acid-activated farnesoid X receptor regulates hydrogen sulfide production and hepatic microcirculation. World J Gastroenterol 2009; 15(17): 2097-2108
URL: https://www.wjgnet.com/1007-9327/full/v15/i17/2097.htm
DOI: https://dx.doi.org/10.3748/wjg.15.2097