Effect of 5-FU on modulation of disarrangement of immune-associated cytokines in experimental acute pancreatitis

Table 1 Change of level of pro-inflammatory cytokines in serum

Group	IL-1 (ng/mL)	IL-6 (IU/mL)	TNF (IU/mL)
A	0.28 ± 0.06	34.5 ± 6.40	11.82 ± 1.87
B  (2 h)	1.02 ± 0.121	98.83 ± 12.431	43.67 ± 5.721
(6 h)	1.13 ± 0.171	101.0 ± 15.071	48.67 ± 5.321
(24 h)	1.15 ± 0.131	127.17 ± 13.911	55.33 ± 12.791
C (2 h)	0.80 ± 0.0712	76.33 ± 7.4212	35.33 ± 4.501
(6 h)	0.70 ± 0.0612	74.33 ± 11.0212	31.17 ± 4.5412
(24 h)	1.02 ± 0.181	112.67 ± 20.061	42.33 ± 11.641

A: Sham operation Group without acute pancreatitis and drug injection; B: Acute pancreatitis Group; C: Acute pancreatitis with 5-FU group. 2 h, 6 h, 24 h: 2 h, 6 h, 24 h after operation.

¹Compared to sham operation Group (Group A), P < 0.05;

²Compared to pancreatitis Group (Group B), P < 0.05.