Expression of phosphatase regenerating liver 3 is an independent prognostic indicator for gastric cancer

Table 2 Multivariate analysis of PRL-3 expression by Cox proportional hazard model

Factors	Overall survival						Disease-free survival
	All patients (n = cases)			Curatively resected (n = 200)			Curatively resected (n = 200)
	P	Relative risk	95% CI	P	Relative risk	95% CI	P	Relative risk	95% CI
PRL-3	< 0.001	1.76	1.30-2.40	< 0.001	2.35	1.54-3.59	< 0.001	2.46	1.62-3.73
T	< 0.001	3.16	1.79-5.58	0.003	3.04	1.47-6.29	0.004	2.76	1.38-5.52
N	< 0.001	3.29	1.93-5.60	< 0.001	3.99	2.21-7.20	< 0.001	4.67	2.59-8.43
D	0.04	1.38	1.01-1.88	0.32	1.23	0.82-1.87	0.015	1.69	1.11-2.57
S	< 0.001	2.24	1.54-3.26	-	-	-	-	-	-

PRL-3 expression, positive vs negative; T: Depth of invasion, T3-4 vs T1-2; N: Lymph node metastasis, present vs absent; D: Tumor size, ≥ 5 cm vs < 5 cm; S: Surgical curability, palliative vs curative.