Expression of phosphatase regenerating liver 3 is an independent prognostic indicator for gastric cancer

Table 1 Association between PRL-3 expression and clinicopathological features

Factors	Patients	PRL-3 expression		P value
		Positive (n = 127)	Negative (n = 266)
Gender
Male	194	85	109	NS
Female	99	42	57
Age (yr)
< 60	149	66	83	NS
≥ 60	144	61	83
Tumor size (cm)
≥ 5	118	63	55	0.004
< 5	175	64	111
Depth of invasion
T1	22	5	17	0.008a
T2	46	15	31	0.009b
T3	175	77	98	0.042c
T4	50	30	20
Lymph node metastasis
N0	82	30	52	< 0.0001d
N1	120	42	78
N2	51	33	18
N3	40	22	18
Distant metastasis
Present	42	21	21	NS
Absent	251	106	145
Vascular/lymphatic invasion
Present	162	89	73	< 0.0001
Absent	131	38	93
Differentiation
Poor	194	91	103	NS
Well/Moderate	99	36	63
Surgical curability
Curative	200	79	121	NS
Not curative	93	48	45
Recurrencee
Absent	177	63	114	0.002
Present	23	16	7
TNM stages
I	42	13	29	0.007f
II	52	17	35	0.008g
III	99	43	56
IV	100	54	46

NS: Not significant;

^aT1-T2 vs T3-T4;

^bT1-T3 vs T4;

^cT1 vs T2-4;

^dN0-N1 vs N2-N3;

^e200 cases received curative surgery;

^fI-II vs III-IV;

^gI-III vs IV.