Interleukin-1 and TNF-α polymorphisms and Helicobacter pylori in a Brazilian Amazon population

Table 5 Association of polymorphism for IL-RN gene and anti-CagA antibodies with histopathological findings from patients

IL1-RN	CagA	DI		OR (95% CI)	P	NA		OR (95% CI)	P	Metaplasia		OR (95% CI)	P
		1	2 and 3			1	2 and 3			+	-
1/1	(-)	13	2	-	-	12	3	-	-	1	14	-	-
2* carrier	(-)	9	1	0.722a	0.706	8	2	1a	0.609	2	8	3.5a	0.706
1/1	(+)	24	34	9.2 00 (1.90-44.606)	0.004	26	32	4.923 (1.254-19.314)	0.032	17	41	5.804 (0.706-47.693)	0.139
2* carrier	(+)	20	63	20.475 (4.253-98.556)	0.001	23	60	10.434 (2.695-40.388)	0.003	35	58	8.448 (1.064-67.065)	0.038

DI: Degree of inflammation; NA: Neutrophilic activity. Histopathological parameters: 1: Light; 2: Moderate; 3: Intense.

^aThe confidence interval was not calculated, since, n₁p₁q₁ < 5 or n₂p₂q₂ < 5.