Interleukin-1 and TNF-α polymorphisms and Helicobacter pylori in a Brazilian Amazon population

Table 4 Combined risk of polymorphism in the IL1-RN gene and IgG CagA antibody for development of gastric ulcers and adenogastric carcinoma

IL1-RN	CagA	Control	GU	ORa (95% IC)	P	AC	ORb (95% IC)	P
1/1	(-)	15 (24%)	2 (6%)	Ref.	-	1 (4%)	Ref.	-
2* carrier	(-)	8 (13%)	2 (6%)	1.875c	0.983	1 (4%)	1.875c	0.735
1/1	(+)	21 (35%)	9 (27%)	3.214 (0.605-17.063)	0.289	8 (30%)	5.714 (0.644-50.648)	0.185
2* carrier	(+)	17 (28%)	20 (61%)	8.823 (1.762-44.181)	0.008	19 (62%)	16.764 (1.997-140.707)	0.004
Total		61	33			29

GU: Gastric ulcer; AC: Adenogastric carcinoma.

^aControl x GU;

^bControl x AC;

^cThe confidence interval was not calculated, since, n₁p₁q₁ < 5 or n₂p₂q₂ < 5.