Interleukin-1 and TNF-α polymorphisms and Helicobacter pylori in a Brazilian Amazon population

Table 2 Comparison of genotype frequencies for the polymorphisms of IL-1β genes studied with results of other studies in different ethnic and population groups n (%)

Genotypes	Pará (Brazil)	Minas Gerais (Brazil)	Caucasians	Asians
IL-1β-31
TT	9	102 (35.8)1	7 (12)2	7 (4)4
TC	23	138 (48.4)	21 (36)	34 (20)
CC	68	45 (15.8)	30 (52)	128 (76)
P value	Reference	0.001	NS	NS
IL-1β-511
CC	31	108 (37.9)1	29 (50)2	34 (20)4
CT	46	137 (48.1)	21 (36)	97 (57)
TT	23	40 (14)	8 (14)	38 (23)
P value	Reference	NS	NS	NS
IL-1RN
11	58	175 (61.4)1	37 (64)2	163 (96)4
12	36	92 (32.3)	14 (24)	4 (3)
22	6	18 (6.3)	17 (10)	2 (1)
P value	Reference	NS	NS	0.001
TNF-α-308
GG	86	223 (78.3)1	152 (72)3	274 (91.3)5
GA	13	54 (18.9)	52 (25)	24 (8)
AA	1	8 (2.8)	6 (3)	2 (0.7)
P value	Reference	NS	0.025	NS

G Test: Our study versus other papers.

¹Queiroz et al[25] 2004;

²El-Omar et al[7] 2000;

³El-Omar et al[24] 2003;

⁴Zeng et al[23] 2003;

⁵Yea et al[11] 2001. NS: Not significant.