Curcumin suppresses PPARδ expression and related genes in HT-29 cells

Figure 3 Curcumin inhibits the expression of PPARδ in HT-29 cells. A: Real-time quantitative RT-PCR indicated that curcumin markedly reduced the level of PPARδ mRNA. Values are % reduction in PPARδ mRNA fold changes caused by curcumin compared with cells without curcumin treatment. Values are mean ± SD from three samples per group. GAPDH was used as an internal control; B: The effects of curcumin on the level of PPARδ protein were determined by Western blotting. β-actin was used as an internal marker. (^aP < 0.05 vs control; ^bP < 0.01 vs control).