Hepatitis C virus and ethanol alter antigen presentation in liver cells

doi:10.3748/wjg.15.1201

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Mar 14, 2009 (publication date) through Nov 3, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 14, 2009; 15(10): 1201-1208
Published online Mar 14, 2009. doi: 10.3748/wjg.15.1201

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Figure 1 Alcohol (ethanol) reduces antigen presentation on HCV-infected liver cells. HCV interferes with the capacity of professional antigen presenting cells (APC) to prime the immune response. Ethanol (EtOH) further dysregulates antigen presentation, suppressing both MHC class I-restricted antigen presentation on infected hepatocytes and MHC class II-restricted antigen presentation on APC.

Citation: Osna NA. Hepatitis C virus and ethanol alter antigen presentation in liver cells. World J Gastroenterol 2009; 15(10): 1201-1208
URL: https://www.wjgnet.com/1007-9327/full/v15/i10/1201.htm
DOI: https://dx.doi.org/10.3748/wjg.15.1201