Overlap of reflux and eosinophilic esophagitis in two patients requiring different therapies: A review of the literature

Figure 1 Case 1. A: Emergency endoscopy showing a meat bolus impacted at mid-distal esophagus with normal mucosa; B: Esophageal manometry demonstrated that two thirds of all contractions in the distal esophagus were simultaneous or interrupted contraction waves; C: Prominent eosinophil microabscesses in upper-mid esophagus biopsies (HE, × 100). In the box and on top of the image, a dense eosinophilic infiltrate (31eo/HPF × 400) predominantly spread over the superficial layers can be observed (HE, × 200); D: Normal upper-mid squamous epithelium after PPI therapy (HE, × 100).