Activator protein-1 involved in growth inhibition by RASSF1A gene in the human gastric carcinoma cell line SGC7901

Figure 3 The over-expression of RASSF1A inhibited the AP-1 activity in gastric cancer cell line SGC7901. A: The over-expression of RASSF1A inhibited the AP-1 DNA binding activity measured by EMSA; B: The over-expression of RASSF1A inhibited the c-Fos but not c-Jun expression in nuclear extract of SGC7901 cells. (Western blotting, DAB staining); C: The over-expression of RASSF1A inhibited the c-Fos expression in nuclear of SGC7901 cells (immunocytochemistry, DAB staining, × 400); D: The over-expression of RASSF1A had no influence on the c-Jun expression in nuclear of SGC7901 cells (immunocytochemistry, DAB staining, × 400).