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©2008 The WJG Press and Baishideng.
World J Gastroenterol. Mar 7, 2008; 14(9): 1444-1449
Published online Mar 7, 2008. doi: 10.3748/wjg.14.1444
Published online Mar 7, 2008. doi: 10.3748/wjg.14.1444
Table 6 Probability ratios for the combinations of ADH1B, CYP2E1 and ALDH2 genotypes among moderate-to-heavy drinkers, n (%)
| Combined genotypes | Genotype | Cases (n = 80) | Controls (n = 480) | OR | 95% CI | |
| ALDH2 + ADH1B | ALDH2*1/1 +ADH1B*1/2 +2/2 | 28 (35.0) | 144 (30.0) | 1 | ||
| ALDH2*1/2 + | 15 (18.8) | 27 (1.9) | 7.46 | 3.28-18.32 | ||
| ADH1B*1/1 | ||||||
| ALDH2 + CYP2E1 | ALDH2*1/1 +CYP2E1*c1/c2 +c2/c2 | 10 (12.5) | 60 (12.5) | 1 | ||
| ALDH2*1/2 +CYP2E1*c1/c1 | 32 (40.0) | 15 (3.1) | 6.82 | 1.44-9.76 | ||
| ADH1B + CYP2E1 | ADH1B*1/2 +2/2 +CYP2E1*c1/c2 +c2/c2 | 12 (15.0) | 36 (2.5) | 1 | ||
| ADH1B*1/1 +CYP2E1*c1/c1 | 14 (17.5) | 66 (13.8) | 6 |
- Citation: Guo YM, Wang Q, Liu YZ, Chen HM, Qi Z, Guo QH. Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males. World J Gastroenterol 2008; 14(9): 1444-1449
- URL: https://www.wjgnet.com/1007-9327/full/v14/i9/1444.htm
- DOI: https://dx.doi.org/10.3748/wjg.14.1444