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©2008 The WJG Press and Baishideng.
World J Gastroenterol. Mar 7, 2008; 14(9): 1444-1449
Published online Mar 7, 2008. doi: 10.3748/wjg.14.1444
Published online Mar 7, 2008. doi: 10.3748/wjg.14.1444
Table 4 Genotypes of ALDH2, ADH2 and P4502E1, n (%)
| Genotype | Cases | Controls | P | OR | 95% CI |
| (n = 80) | (n = 480) | ||||
| ALDH2 genotype | |||||
| 1/1 | 37 (46.3) | 252 (52.5) | 1 | ||
| 1/2 | 43 (53.7) | 195 (40.6) | 0.094 | 2.89 | 1.11-5.64 |
| 2/2 | 0 (0.0) | 33 (6.9) | |||
| ADH1B genotype | |||||
| 1/1 | 17 (21.3) | 24 (5.0) | 1 | ||
| 1/ 2 | 25 (31.3) | 168 (35.0) | < 0.0001 | 3.67 | 1.26-8.73 |
| 2/2 | 38 (47.5) | 288 (60.0) | < 0.0001 | 1.46 | 0.71-2.59 |
| CYP2E1 Pst I/Rsa I | |||||
| c2/c2 | 7 (8. 8) | 75 (15.6) | 1 | ||
| c1/c2 | 16 (20.0) | 180 (37.5) | 0.918 | ||
| c1/c1 | 57 (71.3) | 225 (46.9) | 0.014 | 2.82 | 1.23-6.55 |
- Citation: Guo YM, Wang Q, Liu YZ, Chen HM, Qi Z, Guo QH. Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males. World J Gastroenterol 2008; 14(9): 1444-1449
- URL: https://www.wjgnet.com/1007-9327/full/v14/i9/1444.htm
- DOI: https://dx.doi.org/10.3748/wjg.14.1444