Gastric motor effects of ghrelin and growth hormone releasing peptide 6 in diabetic mice with gastroparesis

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Mar 7, 2008 (publication date) through Dec 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 7, 2008; 14(9): 1419-1424
Published online Mar 7, 2008. doi: 10.3748/wjg.14.1419

Table 2 Effect of GHS-R agonists on the carbachol (0.1 &mgr;mol/L)-induced contractile amplitudes of DM mouse fundic strips

Group	Spontaneous contractile amplitude of DM mouse fundic strips (mg)
Group	0	0.01&mgr;mol/L	0.1&mgr;molL	1&mgr;mol/L	10&mgr;mol/L
Ghrelin + carbachol (0.1 &mgr;mol/L)	60.4 ± 1.21	61.3 ± 1.52	65.7 ± 1.16^a	70.0 ± 1.58^a	78.0 ± 1.56^a
GHRP-6 + carbachol (0.1 &mgr;mol/L)	60.4 ± 1.21	62.3 ± 2.14	65.4 ± 1.24^a	72.0 ± 1.42^a	82.0 ± 1.75^a

^aP < 0.05, vs carbachol (0.1 &mgr;mol/L)-induced contraction amplitude of the DM mouse fundic strips.

Citation: Qiu WC, Wang ZG, Wang WG, Yan J, Zheng Q. Gastric motor effects of ghrelin and growth hormone releasing peptide 6 in diabetic mice with gastroparesis. World J Gastroenterol 2008; 14(9): 1419-1424
URL: https://www.wjgnet.com/1007-9327/full/v14/i9/1419.htm
DOI: https://dx.doi.org/10.3748/wjg.14.1419