Intestinal permeability and its association with the patient and disease characteristics in Crohn’s disease

Table 5 Assessment of the effect of disease and patients characteristics on log LMR using multiple regression analysis

Variable	Regression co-efficientβ(95% CI)
	Unadjusted	Adjusted
Sex
Females1
Males	0.39 (0.089, 0.69)	0.429 (0.130, 0.727)a
Area
Small intestine only1
Large intestine only	-0.284 (-0.764, 0.196)	0.002 (-0.539, 0.543)
Ileo-colonic	0.475 (-0.020, 0.971)	0.579 (0.065, 1.09)a
Behaviour
Non-fistulizing non-stricturing1
Stricturing disease	0.587 (0.230, 0.945)	-0.237 (-0.763, 0.288)
Fistulizing disease	0.152 (-0.366, 0.670)	0.085 (-0.457, 0.628)
Upper GI involvement
Absent1
Present	0.437 (0.019, 0.856)	0.233 (-0.163, 0.630)

R² = 23%,

^aP < 0.05, significant sqrt-square-root transformation.

¹Reference category; β: Regression coefficient; CI: Confidence interval.