Ameliorative effects of bombesin and neurotensin on trinitrobenzene sulphonic acid-induced colitis, oxidative damage and apoptosis in rats

Table 3 Comparison of macroscopic and microscopic colonic damage scores

Colonic damage score		Group I Control	Group II Colitis	Group III BBS	Group IV NTS	Group V BBS and NTS	P
Macroscopic score	mean ± SD	0.3 ± 0.48	7.3 ± 0.94	2.1 ± 0.87	3.7 ± 0.94	2.1 ± 0.87	< 0.01
	Median (Min-Max)	0 (0.0-1.0)b	7 (6.0-9.0)d	2 (1.0-3.0)b	4 (2.0-5.0)f	2 (1.0-3.0)b
Microscopic score	mean ± SD	0.4 ± 0.69	5.2 ± 0.78	2.0 ± 0.66	3.3 ± 0.82	1.8 ± 0.63	< 0.01
	Median (Min-Max)	0 (0.0-2.0)b	5 (4.0-6.0)d	2 (1.0-3.0)b	3.5 (2.0-4.0)f	2 (1.0-3.0)b

Data are expressed as means ± SD and median (min-max).

^bP < 0.01 vs colitis and NTS;

^dP < 0.01 vs BBS, NTS and BBS and NTS;

^fP < 0.01 vs colitis, control, BBS and BBS and NTS. BBS: Bombesin; NTS: Neurotensin.